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10.1016/j.mib.2011.10.007

http://scihub22266oqcxt.onion/10.1016/j.mib.2011.10.007
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C4476652!4476652 !22055570
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suck abstract from ncbi

pmid22055570
      Curr+Opin+Microbiol 2012 ; 15 (1 ): 78-84
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  • Plasticity in mast cell responses during bacterial infections #MMPMID22055570
  • Chan CY ; St John AL ; Abraham SN
  • Curr Opin Microbiol 2012[Feb]; 15 (1 ): 78-84 PMID22055570 show ga
  • Mast cells (MCs) have been implicated in orchestrating the host's early innate immune and adaptive immune responses in several models of acute bacterial infections. Most of this activity results in early clearance of the bacteria and timely resolution of infection. However, during chronic infections because of the prolonged nature of MC-bacterial interactions, the role of the MC in determining the fate of infection is markedly more complex. Depending on the nature of the pathogen, severity of infection, and its association with a preexisting inflammatory disease, MCs may promote rather than contain chronic infections and exacerbate their pathological sequellae.
  • |Animals [MESH]
  • |Bacteria/*immunology/*pathogenicity [MESH]
  • |Bacterial Infections/*immunology/*pathology [MESH]
  • |Humans [MESH]
  • |Mast Cells/*immunology/*microbiology [MESH]
  • |Mice [MESH]


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