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2015 ; 7
(2
): 152-68
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Plasmonic biosensors
#MMPMID25377594
Hill RT
Wiley Interdiscip Rev Nanomed Nanobiotechnol
2015[Mar]; 7
(2
): 152-68
PMID25377594
show ga
The unique optical properties of plasmon resonant nanostructures enable
exploration of nanoscale environments using relatively simple optical
characterization techniques. For this reason, the field of plasmonics continues
to garner the attention of the biosensing community. Biosensors based on
propagating surface plasmon resonances (SPRs) in films are the most
well-recognized plasmonic biosensors, but there is great potential for the new,
developing technologies to surpass the robustness and popularity of film-based
SPR sensing. This review surveys the current plasmonic biosensor landscape with
emphasis on the basic operating principles of each plasmonic sensing technique
and the practical considerations when developing a sensing platform with the
various techniques. The 'gold standard' film SPR technique is reviewed briefly,
but special emphasis is devoted to the up-and-coming localized surface plasmon
resonance and plasmonically coupled sensor technology.