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10.1016/j.semcdb.2016.04.010 http://scihub22266oqcxt.onion/10.1016/j.semcdb.2016.04.010 C5071175!5071175 !27108805     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27108805 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27108805 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Semin+Cell+Dev+Biol 2016 ; 59 (ä): 99-109 Nephropedia Template TP {{tp|p=27108805 |t=2016. Planar cell polarity (PCP) proteins and spermatogenesis |pdf=|usr=}}{{27108805 }} gab.com Text Planar cell polarity (PCP) proteins and spermatogenesis JO: Semin Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=27108805 #FOAvip In adult mammalian testes, spermatogenesis is comprised of several discrete cellular events that work in tandem to support the transformation and differentiation of diploid spermatogonia to haploid spermatids in the seminiferous epithelium during the seminiferous epithelial cycle. These include: self-renewal of spermatogonial stem cells via mitosis and their transformation into differentiated spermatogonia, meiosis I/II, spermiogenesis and the release of sperms at spermiation. Studies have shown that these cellular events are under precise and coordinated controls of multiple proteins and signaling pathways. These events are also regulated by polarity proteins that are known to confer classical apico-basal (A/B) polarity in other epithelia. Furthermore, spermatid development is likely supported by planar cell polarity (PCP) proteins since polarized spermatids are aligned across the plane of seminiferous epithelium in an orderly fashion, analogous to hair cells in the cochlea of the inner ear. Thus, the maximal number of spermatids can be packed and supported by a fixed population of differentiated Sertoli cells in the limited space of the seminiferous epithelium in adult testes. In this review, we briefly summarize recent findings regarding the role of PCP proteins in the testis. This information should be helpful in future studies to better understand the role of PCP proteins in spermatogenesis. Twit Text FOAVip Planar cell polarity (PCP) proteins and spermatogenesis ????Semin Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=27108805 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27108805 #FOAvip English Wikipedia <ref>{{Cite pmid|27108805 }}</ref> Planar cell polarity (PCP) proteins and spermatogenesis #MMPMID27108805 Chen H ; Cheng CY Semin Cell Dev Biol 2016[Nov]; 59 (ä): 99-109 PMID27108805 show ga In adult mammalian testes, spermatogenesis is comprised of several discrete cellular events that work in tandem to support the transformation and differentiation of diploid spermatogonia to haploid spermatids in the seminiferous epithelium during the seminiferous epithelial cycle. These include: self-renewal of spermatogonial stem cells via mitosis and their transformation into differentiated spermatogonia, meiosis I/II, spermiogenesis and the release of sperms at spermiation. Studies have shown that these cellular events are under precise and coordinated controls of multiple proteins and signaling pathways. These events are also regulated by polarity proteins that are known to confer classical apico-basal (A/B) polarity in other epithelia. Furthermore, spermatid development is likely supported by planar cell polarity (PCP) proteins since polarized spermatids are aligned across the plane of seminiferous epithelium in an orderly fashion, analogous to hair cells in the cochlea of the inner ear. Thus, the maximal number of spermatids can be packed and supported by a fixed population of differentiated Sertoli cells in the limited space of the seminiferous epithelium in adult testes. In this review, we briefly summarize recent findings regarding the role of PCP proteins in the testis. This information should be helpful in future studies to better understand the role of PCP proteins in spermatogenesis. |*Cell Polarity [MESH] |*Spermatogenesis [MESH] |Animals [MESH] |Humans [MESH] |Male [MESH] |Models, Biological [MESH] |Proteins/*metabolism [MESH] |Signal Transduction [MESH]Planar cell polarity (PCP) proteins and spermatogenesis (epmc).pdf DeepDyve Pubget Overpricing