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2017 ; 2017
(ä): 5610945
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Placental Chorangiosis: Increased Risk for Cesarean Section
#MMPMID28607782
Petersen SS
; Khangura R
; Davydov D
; Zhang Z
; Sangha R
Case Rep Obstet Gynecol
2017[]; 2017
(ä): 5610945
PMID28607782
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We describe a patient with Class C diabetes who presented for nonstress testing
at 36 weeks and 4 days of gestation with nonreassuring fetal heart tones (NRFHT)
and oligohydramnios. Upon delivery, thrombosis of the umbilical cord was grossly
noted. Pathological analysis of the placenta revealed chorangiosis, vascular
congestion, and 40% occlusion of the umbilical vein. Chorangiosis is a vascular
change of the placenta that involves the terminal chorionic villi. It has been
proposed to result from longstanding, low-grade hypoxia in the placental tissue
and has been associated with such conditions such as diabetes, intrauterine
growth restriction (IUGR), and hypertensive conditions in pregnancy. To
characterize chorangiosis and its associated obstetric outcomes we identified 61
cases of "chorangiosis" on placental pathology at Henry Ford Hospital from 2010
to 2015. Five of these cases were omitted due to lack of complete records. Among
the 56 cases, the cesarean section rate was 51%, indicated in most cases for
nonreassuring fetal status. Thus, we suggest that chorangiosis, a marker of
chronic hypoxia, is associated with increased rates of cesarean sections for
nonreassuring fetal status because of long standing hypoxia coupled with the
stress of labor.