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10.1177/1535370214538589 http://scihub22266oqcxt.onion/10.1177/1535370214538589 C4156521!4156521 !24912506     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24912506 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24912506 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Exp+Biol+Med+(Maywood) 2014 ; 239 (9 ): 1203-14 Nephropedia Template TP {{tp|p=24912506 |t=2014. Physiology and metabolism of tissue-engineered skeletal muscle |pdf=|usr=}}{{24912506 }} gab.com Text Physiology and metabolism of tissue-engineered skeletal muscle JO: Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=24912506 #FOAvip Skeletal muscle is a major target for tissue engineering, given its relative size in the body, fraction of cardiac output that passes through muscle beds, as well as its key role in energy metabolism and diabetes, and the need for therapies for muscle diseases such as muscular dystrophy and sarcopenia. To date, most studies with tissue-engineered skeletal muscle have utilized murine and rat cell sources. On the other hand, successful engineering of functional human muscle would enable different applications including improved methods for preclinical testing of drugs and therapies. Some of the requirements for engineering functional skeletal muscle include expression of adult forms of muscle proteins, comparable contractile forces to those produced by native muscle, and physiological force-length and force-frequency relations. This review discusses the various strategies and challenges associated with these requirements, specific applications with cultured human myoblasts, and future directions. Twit Text FOAVip Physiology and metabolism of tissue-engineered skeletal muscle ????Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=24912506 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24912506 #FOAvip English Wikipedia <ref>{{Cite pmid|24912506 }}</ref> Physiology and metabolism of tissue-engineered skeletal muscle #MMPMID24912506 Cheng CS ; Davis BN ; Madden L ; Bursac N ; Truskey GA Exp Biol Med (Maywood) 2014[Sep]; 239 (9 ): 1203-14 PMID24912506 show ga Skeletal muscle is a major target for tissue engineering, given its relative size in the body, fraction of cardiac output that passes through muscle beds, as well as its key role in energy metabolism and diabetes, and the need for therapies for muscle diseases such as muscular dystrophy and sarcopenia. To date, most studies with tissue-engineered skeletal muscle have utilized murine and rat cell sources. On the other hand, successful engineering of functional human muscle would enable different applications including improved methods for preclinical testing of drugs and therapies. Some of the requirements for engineering functional skeletal muscle include expression of adult forms of muscle proteins, comparable contractile forces to those produced by native muscle, and physiological force-length and force-frequency relations. This review discusses the various strategies and challenges associated with these requirements, specific applications with cultured human myoblasts, and future directions. |*Tissue Engineering/instrumentation/methods [MESH] |Animals [MESH] |Drug Evaluation, Preclinical [MESH] |Humans [MESH] |Muscle, Skeletal/*metabolism/pathology [MESH] |Muscular Dystrophies/drug therapy/metabolism/pathology [MESH] |Myoblasts, Skeletal/*metabolism/pathology [MESH] |Rats [MESH]Physiology and metabolism of tissue-engineered skeletal muscle (epmc).pdf DeepDyve Pubget Overpricing