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10.4161/21541272.2014.944039

http://scihub22266oqcxt.onion/10.4161/21541272.2014.944039
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suck abstract from ncbi


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pmid25483405
      Transcription 2014 ; 5 (4 ): e944039
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  • Pervasive transcription: detecting functional RNAs in bacteria #MMPMID25483405
  • Lybecker M ; Bilusic I ; Raghavan R
  • Transcription 2014[]; 5 (4 ): e944039 PMID25483405 show ga
  • Pervasive, or genome-wide, transcription has been reported in all domains of life. In bacteria, most pervasive transcription occurs antisense to protein-coding transcripts, although recently a new class of pervasive RNAs was identified that originates from within annotated genes. Initially considered to be non-functional transcriptional noise, pervasive transcription is increasingly being recognized as important in regulating gene expression. The function of pervasive transcription is an extensively debated question in the field of transcriptomics and regulatory RNA biology. Here, we highlight the most recent contributions addressing the purpose of pervasive transcription in bacteria and discuss their implications.
  • |Bacteria/genetics/metabolism [MESH]
  • |Bacterial Proteins/metabolism [MESH]
  • |Host Factor 1 Protein/metabolism [MESH]
  • |RNA Processing, Post-Transcriptional [MESH]
  • |RNA, Antisense/metabolism [MESH]
  • |RNA, Bacterial/*metabolism [MESH]
  • |Ribonuclease III/metabolism [MESH]
  • |Sigma Factor/metabolism [MESH]


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