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10.1177/1066896915591272 http://scihub22266oqcxt.onion/10.1177/1066896915591272 C4641786!4641786!26085647     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26085647.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Surg+Pathol 2015 ; 23 (8): 638-48 Nephropedia Template TP {{tp|p=26085647|t=2015. Pericyte Antigens in Perivascular Soft Tissue Tumors |pdf=|usr=}}{{26085647}} gab.com Text Pericyte Antigens in Perivascular Soft Tissue Tumors JO: Int J Surg Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26085647 #FOAvip Introduction: Perivascular soft tissue tumors are relatively uncommon neoplasms of unclear line of differentiation, although most are presumed to originate from pericytes or modified perivascular cells. Among these, glomus tumor, myopericytoma, and angioleiomyoma share a spectrum of histologic findings and a perivascular growth pattern. In contrast, solitary fibrous tumor (previously termed hemangiopericytoma) was once hypothesized to have pericytic differentiation. Methods: Here, we systematically examine pericyte immunohistochemical markers among glomus tumor (including malignant glomus tumor), myopericytoma, angioleiomyoma, and solitary fibrous tumor. Immunohistochemical staining and semiquantification was performed using well-defined pericyte antigens, including ?SMA, CD146, and PDGFR?. Results: Glomus tumor and myopericytoma demonstrate diffuse staining for all pericyte markers, including immunohistochemical reactivity for ?SMA, CD146, and PDGFR?. Malignant glomus tumors all showed some degree of pericyte marker immunoreactivity, although it was significantly reduced. Angioleiomyoma shared a similar ?SMA + CD146 + PDGFR?+ immunophenotype; however, this was predominantly seen in the areas of perivascular tumor growth. Solitary fibrous tumors showed patchy PDGFR? immunoreactivity only. Discussion: In summary, pericyte marker expression is a ubiquitous finding in glomus tumor, myopericytoma, and angioleiomyoma. Malignant glomus tumor shows a comparative reduction in pericyte marker expression, which may represent partial loss of pericytic differentiation. Pericyte markers are essentially not seen in solitary fibrous tumor. The combination of ?SMA, CD146, and PDGFR? immunohistochemical stainings may be of utility for the evaluation of pericytic differentiation in soft tissue tumors. Twit Text FOAVip Pericyte Antigens in Perivascular Soft Tissue Tumors ????Int J Surg Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26085647 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26085647 #FOAvip English Wikipedia <ref>{{Cite pmid|26085647}}</ref> Pericyte Antigens in Perivascular Soft Tissue Tumors #MMPMID26085647 Shen J; Shrestha S; Yen YH; Asatrian G; Mravic M; Soo C; Ting K; Dry SM; Peault B; James AW Int J Surg Pathol 2015[Dec]; 23 (8): 638-48 PMID26085647show ga Introduction: Perivascular soft tissue tumors are relatively uncommon neoplasms of unclear line of differentiation, although most are presumed to originate from pericytes or modified perivascular cells. Among these, glomus tumor, myopericytoma, and angioleiomyoma share a spectrum of histologic findings and a perivascular growth pattern. In contrast, solitary fibrous tumor (previously termed hemangiopericytoma) was once hypothesized to have pericytic differentiation. Methods: Here, we systematically examine pericyte immunohistochemical markers among glomus tumor (including malignant glomus tumor), myopericytoma, angioleiomyoma, and solitary fibrous tumor. Immunohistochemical staining and semiquantification was performed using well-defined pericyte antigens, including ?SMA, CD146, and PDGFR?. Results: Glomus tumor and myopericytoma demonstrate diffuse staining for all pericyte markers, including immunohistochemical reactivity for ?SMA, CD146, and PDGFR?. Malignant glomus tumors all showed some degree of pericyte marker immunoreactivity, although it was significantly reduced. Angioleiomyoma shared a similar ?SMA + CD146 + PDGFR?+ immunophenotype; however, this was predominantly seen in the areas of perivascular tumor growth. Solitary fibrous tumors showed patchy PDGFR? immunoreactivity only. Discussion: In summary, pericyte marker expression is a ubiquitous finding in glomus tumor, myopericytoma, and angioleiomyoma. Malignant glomus tumor shows a comparative reduction in pericyte marker expression, which may represent partial loss of pericytic differentiation. Pericyte markers are essentially not seen in solitary fibrous tumor. The combination of ?SMA, CD146, and PDGFR? immunohistochemical stainings may be of utility for the evaluation of pericytic differentiation in soft tissue tumors. äPericyte Antigens in Perivascular Soft Tissue Tumors (epmc).pdf DeepDyve Pubget Overpricing