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2016 ; 2016
(ä): 1489204
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Penis Allotransplantation in Beagle Dog
#MMPMID26977412
Zhao Y
; Hu W
; Zhang L
; Guo F
; Wang W
; Wang B
; Zhang C
Biomed Res Int
2016[]; 2016
(ä): 1489204
PMID26977412
show ga
This is an original research of penis allotransplantation. The paper presents an
experiment allogenic penis transplantation model in Beagles, with a focus on
recovery of blood supply and changes in tissue architecture. Twenty adult Beagles
were allocated to 10 pairs for penile transplantation. After operation, the skin
and glans were observed. If adverse symptoms occurred, the transplanted penis was
resected and pathologically examined. Frequency of urination, urinary stream, and
patency level were recorded 7 days after transplantation. Cystourethrography was
performed on Day 10. The transplanted penises were resected on Day 14 for
pathological examination. The research showed that transplanted penises survived
after allotransplantation, and the dogs regained urination ability. Penis
autotransplantation in Beagles is feasible. This preliminary study shows a
potential for application of this new procedure for penis transplantation in
humans.