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2015 ; 7
(11
): 279-88
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Pelvic radiation therapy: Between delight and disaster
#MMPMID26649150
Morris KA
; Haboubi NY
World J Gastrointest Surg
2015[Nov]; 7
(11
): 279-88
PMID26649150
show ga
In the last few decades radiotherapy was established as one of the best and most
widely used treatment modalities for certain tumours. Unfortunately that came
with a price. As more people with cancer survive longer an ever increasing number
of patients are living with the complications of radiotherapy and have become, in
certain cases, difficult to manage. Pelvic radiation disease (PRD) can result
from ionising radiation-induced damage to surrounding non-cancerous tissues
resulting in disruption of normal physiological functions and symptoms such as
diarrhoea, tenesmus, incontinence and rectal bleeding. The burden of PRD-related
symptoms, which impact on a patient's quality of life, has been under appreciated
and sub-optimally managed. This article serves to promote awareness of PRD and
the vast potential there is to improve current service provision and research
activities.