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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Pediatr+Genet
2014 ; 3
(4
): 259-69
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Pediatric genetic ocular tumors
#MMPMID27625882
Rouhani B
; Ramasubramanian A
J Pediatr Genet
2014[Dec]; 3
(4
): 259-69
PMID27625882
show ga
Pediatric genetic ocular tumors include malignancies like retinoblastoma and
phakomatosis like neurofibromatosis, tuberous sclerosis, von Hippel-Lindau
syndrome, and nevoid basal cell carcinoma syndrome. It is important to screen for
ocular tumors both for visual prognosis and also for systemic implications. The
phakomatosis comprise of multitude of benign tumors that are aysmptomatic but
their detection can aid in the diagnosis of the syndrome. Retinoblastoma is the
most common malignant intraocular tumor in childhood and with current treatment
modalities, the survival is more than 95%. It is transmitted as an autosomal
dominant fashion and hence the offsprings of all patients with the germline
retinoblastoma need to be screened from birth. This review discusses the various
pediatric genetic ocular tumors discussing the clinical manifestation, diagnosis
and treatment.