Pediatric genetic disorders of lens
#MMPMID27625879
Nihalani BR
J Pediatr Genet
2014[Dec]; 3
(4
): 219-27
PMID27625879
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Pediatric genetic disorders of lens include various cataractous and
non-cataractous anomalies. The purpose of this review is to help determine the
genetic cause based on the lens appearance, ocular and systemic associations.
Children with bilateral cataracts require a comprehensive history, ophthalmic and
systemic examination to guide further genetic evaluation. With advancements in
genetics, it is possible to determine the genetic mutations and assess phenotype
genotype correlation in different lens disorders. The genetic diagnosis helps the
families to better understand the disorder and develop realistic expectations as
to the course of their child's disorder.
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