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10.1007/s11255-014-0808-9

http://scihub22266oqcxt.onion/10.1007/s11255-014-0808-9
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suck abstract from ncbi


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pmid25238890
      Int+Urol+Nephrol 2014 ; 46 Suppl 1 (0 1 ): S11-21
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  • Pathophysiology and animal modeling of underactive bladder #MMPMID25238890
  • Tyagi P ; Smith PP ; Kuchel GA ; de Groat WC ; Birder LA ; Chermansky CJ ; Adam RM ; Tse V ; Chancellor MB ; Yoshimura N
  • Int Urol Nephrol 2014[Sep]; 46 Suppl 1 (0 1 ): S11-21 PMID25238890 show ga
  • While the symptomology of underactive bladder (UAB) may imply a primary dysfunction of the detrusor muscle, insights into pathophysiology indicate that both myogenic and neurogenic mechanisms need to be considered. Due to lack of proper animal models, the current understanding of the UAB pathophysiology is limited, and much of what is known about the clinical etiology of the condition has been derived from epidemiological data. We hereby review current state of the art in the understanding of the pathophysiology of and animal models used to study the UAB.
  • |*Disease Models, Animal [MESH]
  • |Aging/*physiology [MESH]
  • |Animals [MESH]
  • |Animals, Genetically Modified [MESH]
  • |Mice/genetics [MESH]
  • |Muscle, Smooth/*physiopathology/ultrastructure [MESH]
  • |Parkinson Disease/complications [MESH]
  • |Peripheral Nerve Injuries/complications [MESH]
  • |Receptors, Prostaglandin/genetics [MESH]
  • |Receptors, Purinergic/genetics [MESH]
  • |Spinal Cord Injuries/complications [MESH]
  • |Spinal Stenosis/complications [MESH]
  • |Urinary Bladder Diseases/*etiology/*physiopathology [MESH]
  • |Urinary Bladder Neck Obstruction/complications [MESH]


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