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2015 ; 8
(ä): 23-35
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Parallel computing in genomic research: advances and applications
#MMPMID26604801
Ocaña K
; de Oliveira D
Adv Appl Bioinform Chem
2015[]; 8
(ä): 23-35
PMID26604801
show ga
Today's genomic experiments have to process the so-called "biological big data"
that is now reaching the size of Terabytes and Petabytes. To process this huge
amount of data, scientists may require weeks or months if they use their own
workstations. Parallelism techniques and high-performance computing (HPC)
environments can be applied for reducing the total processing time and to ease
the management, treatment, and analyses of this data. However, running
bioinformatics experiments in HPC environments such as clouds, grids, clusters,
and graphics processing unit requires the expertise from scientists to integrate
computational, biological, and mathematical techniques and technologies. Several
solutions have already been proposed to allow scientists for processing their
genomic experiments using HPC capabilities and parallelism techniques. This
article brings a systematic review of literature that surveys the most recently
published research involving genomics and parallel computing. Our objective is to
gather the main characteristics, benefits, and challenges that can be considered
by scientists when running their genomic experiments to benefit from parallelism
techniques and HPC capabilities.