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10.1038/tpj.2015.32 http://scihub22266oqcxt.onion/10.1038/tpj.2015.32 C4819767!4819767 !25939485     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25939485 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Pharmacogenomics+J 2016 ; 16 (2 ): 124-8 Nephropedia Template TP {{tp|p=25939485 |t=2016. PGMD: a comprehensive manually curated pharmacogenomic database |pdf=|usr=}}{{25939485 }} gab.com Text PGMD: a comprehensive manually curated pharmacogenomic database JO: Pharmacogenomics J http://www.kidney.de/pget.php?&tw=1&pmid=25939485 #FOAvip The PharmacoGenomic Mutation Database (PGMD) is a comprehensive manually curated pharmacogenomics database. Two major sources of PGMD data are peer-reviewed literature and Food and Drug Administration (FDA) and European Medicines Agency (EMA) drug labels. PGMD curators capture information on exact genomic location and sequence changes, on resulting phenotype, drugs administered, patient population, study design, disease context, statistical significance and other properties of reported pharmacogenomic variants. Variants are annotated into functional categories on the basis of their influence on pharmacokinetics, pharmacodynamics, efficacy or clinical outcome. The current release of PGMD includes over 117?000 unique pharmacogenomic observations, covering all 24 disease superclasses and nearly 1400 drugs. Over 2800 genes have associated pharmacogenomic variants, including genes in proximity to intergenic variants. PGMD is optimized for use in annotating next-generation sequencing data by providing genomic coordinates for all covered variants, including Single Nucleotide Polymorphisms (SNPs), insertions, deletions, haplotypes, diplotypes, Variable Number Tandem Repeats (VNTR), copy number variations and structural variations. Twit Text FOAVip PGMD: a comprehensive manually curated pharmacogenomic database ????Pharmacogenomics J http://www.kidney.de/pget.php?&tw=1&pmid=25939485 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25939485 #FOAvip English Wikipedia <ref>{{Cite pmid|25939485 }}</ref> PGMD: a comprehensive manually curated pharmacogenomic database #MMPMID25939485 Kaplun A ; Hogan JD ; Schacherer F ; Peter AP ; Krishna S ; Braun BR ; Nambudiry R ; Nitu MG ; Mallelwar R ; Albayrak A Pharmacogenomics J 2016[Apr]; 16 (2 ): 124-8 PMID25939485 show ga The PharmacoGenomic Mutation Database (PGMD) is a comprehensive manually curated pharmacogenomics database. Two major sources of PGMD data are peer-reviewed literature and Food and Drug Administration (FDA) and European Medicines Agency (EMA) drug labels. PGMD curators capture information on exact genomic location and sequence changes, on resulting phenotype, drugs administered, patient population, study design, disease context, statistical significance and other properties of reported pharmacogenomic variants. Variants are annotated into functional categories on the basis of their influence on pharmacokinetics, pharmacodynamics, efficacy or clinical outcome. The current release of PGMD includes over 117?000 unique pharmacogenomic observations, covering all 24 disease superclasses and nearly 1400 drugs. Over 2800 genes have associated pharmacogenomic variants, including genes in proximity to intergenic variants. PGMD is optimized for use in annotating next-generation sequencing data by providing genomic coordinates for all covered variants, including Single Nucleotide Polymorphisms (SNPs), insertions, deletions, haplotypes, diplotypes, Variable Number Tandem Repeats (VNTR), copy number variations and structural variations. |*Databases, Factual [MESH] |*Pharmacogenetics [MESH] |Databases, Genetic [MESH] |Mutation [MESH] |Pharmacokinetics [MESH]PGMD: a comprehensive manually curated pharmacogenomic database (epmc).pdf DeepDyve Pubget Overpricing