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PFAS-contaminated drinking water harms infants #MMPMID41359852
Baluja R; Guo B; Howden W; Langer A; Lemoine D
Proc Natl Acad Sci U S A 2025[Dec]; 122 (50): e2509801122 PMID41359852show ga
There is evidence of widespread human exposure to per- and polyfluoroalkyl substances (PFAS) but limited evidence of the human health impacts of this exposure. Using data on New Hampshire births from 2010-2019, we show that mothers receiving water that had flowed beneath a PFAS-contaminated site, as opposed to comparable mothers receiving water that had flowed toward a PFAS-contaminated site, had 191% [95% CI: 83-298%] higher first-year infant mortality (611 [268-955] additional first-year deaths per 100k births); 168% [42-294%] more births before 28 wk of gestational age (466 [116-817] additional such births per 100k births); and 180% [57-302%] more births with weight below 1,000 g (607 [192-1022] additional such births per 100k births). Extrapolating to the contiguous U.S., PFAS contamination imposes annual social costs of approximately $8 billion. These health costs are substantially larger than current outside estimates of the cost of removing PFAS from the public water supply.
Proc+Natl+Acad+Sci+U+S+A 2025 ; 122 (50): e2509801122
