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2016 ; 6
(ä): 26799
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P-wave Variability and Atrial Fibrillation
#MMPMID27225709
Censi F
; Corazza I
; Reggiani E
; Calcagnini G
; Mattei E
; Triventi M
; Boriani G
Sci Rep
2016[May]; 6
(ä): 26799
PMID27225709
show ga
The analysis of P-wave template has been widely used to extract indices of Atrial
Fibrillation (AF) risk stratification. The aim of this paper was to assess the
potential of the analysis of the P-wave variability over time in patients
suffering from atrial fibrillation. P-wave features extracted from P-wave
template together with novel indices of P-wave variability have been estimated in
a population of patients suffering from persistent AF and compared to those
extracted from control subjects. We quantify the P-wave variability over time
using three algorithms and we extracted three novel indices: one based on the
cross-correlation coefficients among the P-waves (Cross-Correlation Index, CCI),
one associated to variation in amplitude of the P-waves (Amplitude Dispersion
Index, ADI), one sensible to the phase shift among P-waves (Warping Index, WI).
The control group resulted to be characterized by shorter P-wave duration and by
a less amount of fragmentation and variability, respect to AF patients. The
parameter CCI shows the highest sensitivity (97.3%) and a good specificity (95%).
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