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2004 ; Chapter 17
(1
): Unit 17.1
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Overview of protein structural and functional folds
#MMPMID18429251
Sun PD
; Foster CE
; Boyington JC
Curr Protoc Protein Sci
2004[May]; Chapter 17
(1
): Unit 17.1
PMID18429251
show ga
This overview provides an illustrated, comprehensive survey of some commonly
observed protein-fold families and structural motifs, chosen for their functional
significance. It opens with descriptions and definitions of the various elements
of protein structure and associated terminology. Following is an introduction
into web-based structural bioinformatics that includes surveys of interactive web
servers for protein fold or domain annotation, protein-structure databases,
protein-structure-classification databases, structural alignments of proteins,
and molecular graphics programs available for personal computers. The rest of the
overview describes selected families of protein folds in terms of their
secondary, tertiary, and quaternary structural arrangements, including
ribbon-diagram examples, tables of representative structures with references, and
brief explanations pointing out their respective biological and functional
significance.