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10.2217/imt.15.75 http://scihub22266oqcxt.onion/10.2217/imt.15.75 C4681396!4681396 !26598957     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26598957 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26598957 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Immunotherapy 2015 ; 7 (10 ): 1073-104 Nephropedia Template TP {{tp|p=26598957 |t=2015. Overview of current immunotherapeutic strategies for glioma |pdf=|usr=}}{{26598957 }} gab.com Text Overview of current immunotherapeutic strategies for glioma JO: Immunotherapy http://www.kidney.de/pget.php?&tw=1&pmid=26598957 #FOAvip In the last decade, numerous studies of immunotherapy for malignant glioma (glioblastoma multiforme) have brought new knowledge and new hope for improving the prognosis of this incurable disease. Some clinical trials have reached Phase III, following positive outcomes in Phase I and II, with respect to safety and immunological end points. Results are encouraging especially when considering the promise of sustained efficacy by inducing antitumor immunological memory. Progress in understanding the mechanisms of tumor-induced immune suppression led to the development of drugs targeting immunosuppressive checkpoints, which are used in active clinical trials for glioblastoma multiforme. Insights related to the heterogeneity of the disease bring new challenges for the management of glioma and underscore a likely cause of therapeutic failure. An emerging therapeutic strategy is represented by a combinatorial, personalized approach, including the standard of care: surgery, radiation, chemotherapy with added active immunotherapy and multiagent targeting of immunosuppressive checkpoints. Twit Text FOAVip Overview of current immunotherapeutic strategies for glioma ????Immunotherapy http://www.kidney.de/pget.php?&tw=1&pmid=26598957 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26598957 #FOAvip English Wikipedia <ref>{{Cite pmid|26598957 }}</ref> Overview of current immunotherapeutic strategies for glioma #MMPMID26598957 Calinescu AA ; Kamran N ; Baker G ; Mineharu Y ; Lowenstein PR ; Castro MG Immunotherapy 2015[]; 7 (10 ): 1073-104 PMID26598957 show ga In the last decade, numerous studies of immunotherapy for malignant glioma (glioblastoma multiforme) have brought new knowledge and new hope for improving the prognosis of this incurable disease. Some clinical trials have reached Phase III, following positive outcomes in Phase I and II, with respect to safety and immunological end points. Results are encouraging especially when considering the promise of sustained efficacy by inducing antitumor immunological memory. Progress in understanding the mechanisms of tumor-induced immune suppression led to the development of drugs targeting immunosuppressive checkpoints, which are used in active clinical trials for glioblastoma multiforme. Insights related to the heterogeneity of the disease bring new challenges for the management of glioma and underscore a likely cause of therapeutic failure. An emerging therapeutic strategy is represented by a combinatorial, personalized approach, including the standard of care: surgery, radiation, chemotherapy with added active immunotherapy and multiagent targeting of immunosuppressive checkpoints. |*Immune Tolerance [MESH] |*Immunologic Memory [MESH] |Central Nervous System Neoplasms/*immunology/*therapy [MESH] |Clinical Trials as Topic [MESH] |Glioblastoma/*immunology/*therapy [MESH] |Humans [MESH] |Immunotherapy/*methods [MESH] |Precision Medicine [MESH] |Standard of Care [MESH]Overview of current immunotherapeutic strategies for glioma (epmc).pdf DeepDyve Pubget Overpricing