Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\30062135
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Laryngoscope+Investig+Otolaryngol
2018 ; 3
(3
): 198-208
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Otogenic brain abscesses: A systematic review
#MMPMID30062135
Duarte MJ
; Kozin ED
; Barshak MB
; Reinshagen K
; Knoll RM
; Abdullah KG
; Welling DB
; Jung DH
Laryngoscope Investig Otolaryngol
2018[Jun]; 3
(3
): 198-208
PMID30062135
show ga
OBJECTIVE: Otogenic brain abscesses are one of the most significant
life-threatening complications of otologic infections. Given their low
prevalence, otogenic brain abscesses require a high index of suspicion for
diagnosis. In this systematic review, we aim to provide an analysis of otogenic
brain abscesses and describe common clinical signs and symptoms, bacteriology,
location, treatment options, morbidity, and mortality. DATA SOURCES: PubMed,
Cochrane CENTRAL database, Google Scholar, and Scopus. METHODS: A systematic
review of literature was performed using the Preferred Reporting Items for
Systematic Reviews and Meta-analyses recommendations. Variables assessed included
clinical signs and symptoms, bacteriology, location, treatment, morbidity, and
mortality. RESULTS: Twenty-nine studies met inclusion and exclusion criteria,
corresponding to a total of 1307 otogenic abscess cases for review. Fifty-five
percent of abscesses were found in the temporal lobe and 28% in the cerebellum.
Most patients (88.3%) had a history of suppurative chronic otitis media. The most
common symptoms were headache, altered mental status, papilledema, and meningeal
irritation. Fever, nausea, and vomiting affected about 40% of patients. The most
commonly cultured bacterial species was Proteus mirabilis. In addition to
antibiotics, most otogenic brain abscesses were treated by burr hole aspiration.
Average mortality following advent of computed tomography was 8.11%. CONCLUSION:
Although rare, otogenic brain abscesses may occur as a complication of
suppurative otitis media and require a high index of suspicion. Appropriate
imaging studies and multidisciplinary expertise are crucial in the diagnosis and
management. LEVEL OF EVIDENCE: 4.