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10.1155/2015/564934

http://scihub22266oqcxt.onion/10.1155/2015/564934
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suck abstract from ncbi


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pmid26078757
      Int+J+Endocrinol 2015 ; 2015 (ä): 564934
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  • Osteoprotegerin in Cardiometabolic Disorders #MMPMID26078757
  • Pérez de Ciriza C ; Lawrie A ; Varo N
  • Int J Endocrinol 2015[]; 2015 (ä): 564934 PMID26078757 show ga
  • Osteoprotegerin (OPG), a glycoprotein traditionally implicated in bone remodelling, has been recently related to cardiovascular disease (CVD). Human studies show a positive relationship between circulating OPG, vascular damage, and CVD, and as such OPG has emerged as a potential biomarker for CVD. This review focuses on the relationship between circulating OPG and different endocrine cardiometabolic alterations such as type 1 and 2 diabetes. The association of OPG with diabetic complications (neuropathy, nephropathy, or retinopathy) as well as with atherosclerosis, coronary artery calcification, morbidity, and mortality is pointed out. Moreover, OPG modulation by different treatments is also established. Besides, other associated diseases such as obesity, hypertension, and metabolic syndrome, which are known cardiovascular risk factors, are also considered.
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