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2015 ; 6
(3
): 177-9
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Osteopoikilosis: A rare cause of bone pain
#MMPMID26644888
Mahbouba J
; Mondher G
; Amira M
; Walid M
; Naceur B
Caspian J Intern Med
2015[Sum]; 6
(3
): 177-9
PMID26644888
show ga
BACKGROUND: Osteopoikilosis (OPK) is a rare inherited condition of the bones,
transmitted as an autosomal dominant trait characterized by numerous hyperostotic
areas that tend to localize in periarticular osseous regions. It is usually
asymptomatic and is often diagnosed incidentally during x-rays made by other
reasons. We present a case of 34-year-old man suffering from polyarthralgia and
low back pain. CASE PRESENTATION: A 34-year-old male patient, smoking 40 packs
yearly and alcoholic was referred to our department of rheumatology, complaining
of polyarthralgia which started 3 years ago and involving large and small joints.
He reported the presence of pelvic pain mostly located at both hip joints and in
the two ankles. On radiologic examination, numerous, symmetric, well defined,
sclerotic lesions were identified on shoulder, wrist, ankles, pelvis, and on
spine. The size of the lesions varied from 2 to 9 millimeters. These spots were
located on spongious bone tissue, and in the inner bone cortex located
bilaterally in the epiphyses and metaphyses. We concluded the diagnosis of OPK.
His mother was found to have the same lesions without any symptoms. CONCLUSION:
OPK may be an isolated finding or associated with other pathologies, e.g. skin
manifestations, rheumatic and/or skeletal disorders. The main differential
diagnosis is osteoblastic metastasis.