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10.4239/wjd.v6.i18.1345 http://scihub22266oqcxt.onion/10.4239/wjd.v6.i18.1345 C4689779!4689779 !26722618     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26722618 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       World+J+Diabetes 2015 ; 6 (18 ): 1345-54 Nephropedia Template TP {{tp|p=26722618 |t=2015. Osteocalcin as a hormone regulating glucose metabolism |pdf=|usr=}}{{26722618 }} gab.com Text Osteocalcin as a hormone regulating glucose metabolism JO: World J Diabetes http://www.kidney.de/pget.php?&tw=1&pmid=26722618 #FOAvip The number of patients with osteoporosis and diabetes is rapidly increasing all over the world. Bone is recently recognized as an endocrine organ. Accumulating evidence has shown that osteocalcin, which is specifically expressed in osteoblasts and secreted into the circulation, regulates glucose homeostasis by stimulating insulin expression in pancreas and adiponectin expression in adipocytes, resulting in improving glucose intolerance. On the other hand, insulin and adiponectin stimulate osteocalcin expression in osteoblasts, suggesting that positive feedforward loops exist among bone, pancreas, and adipose tissue. In addition, recent studies have shown that osteocalcin enhances insulin sensitivity and the differentiation in muscle, while secreted factors from muscle, myokines, regulate bone metabolism. These findings suggest that bone metabolism and glucose metabolism are associated with each other through the action of osteocalcin. In this review, I describe the role of osteocalcin in the interaction among bone, pancreas, brain, adipose tissue, and muscle. Twit Text FOAVip Osteocalcin as a hormone regulating glucose metabolism ????World J Diabetes http://www.kidney.de/pget.php?&tw=1&pmid=26722618 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26722618 #FOAvip English Wikipedia <ref>{{Cite pmid|26722618 }}</ref> Osteocalcin as a hormone regulating glucose metabolism #MMPMID26722618 Kanazawa I World J Diabetes 2015[Dec]; 6 (18 ): 1345-54 PMID26722618 show ga The number of patients with osteoporosis and diabetes is rapidly increasing all over the world. Bone is recently recognized as an endocrine organ. Accumulating evidence has shown that osteocalcin, which is specifically expressed in osteoblasts and secreted into the circulation, regulates glucose homeostasis by stimulating insulin expression in pancreas and adiponectin expression in adipocytes, resulting in improving glucose intolerance. On the other hand, insulin and adiponectin stimulate osteocalcin expression in osteoblasts, suggesting that positive feedforward loops exist among bone, pancreas, and adipose tissue. In addition, recent studies have shown that osteocalcin enhances insulin sensitivity and the differentiation in muscle, while secreted factors from muscle, myokines, regulate bone metabolism. These findings suggest that bone metabolism and glucose metabolism are associated with each other through the action of osteocalcin. In this review, I describe the role of osteocalcin in the interaction among bone, pancreas, brain, adipose tissue, and muscle. äOsteocalcin as a hormone regulating glucose metabolism (epmc).pdf DeepDyve Pubget Overpricing