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10.1080/21541264.2017.1373209

http://scihub22266oqcxt.onion/10.1080/21541264.2017.1373209
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C5927659!5927659 !29099304
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suck abstract from ncbi


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pmid29099304
      Transcription 2018 ; 9 (3 ): 171-176
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  • Orphan CpG islands as alternative promoters #MMPMID29099304
  • Sarda S ; Hannenhalli S
  • Transcription 2018[]; 9 (3 ): 171-176 PMID29099304 show ga
  • CpG islands (CGIs) are associated with ?60% of mammalian promoters. Most unmethylated CGIs exhibit transcriptional activity, which has led to their co-option as promoters by retrogenes. CGIs may also serve as alternative promoters for downstream genes with methylated promoters, with implications on aberrant activation of oncogenes in cancer phenotypes.
  • |*CpG Islands [MESH]
  • |*DNA Methylation [MESH]
  • |*Promoter Regions, Genetic [MESH]
  • |Animals [MESH]
  • |Evolution, Molecular [MESH]
  • |Gene Expression Regulation, Neoplastic [MESH]
  • |Humans [MESH]
  • |Neoplasms/genetics [MESH]


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