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10.1073/pnas.1610347113 http://scihub22266oqcxt.onion/10.1073/pnas.1610347113 C5056065!5056065 !27663743     free     free     free       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (40 ): 11208-11213 Nephropedia Template TP {{tp|p=27663743 |t=2016. Oriented collagen fibers direct tumor cell intravasation |pdf=|usr=}}{{27663743 }} gab.com Text Oriented collagen fibers direct tumor cell intravasation JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27663743 #FOAvip In this work, we constructed a Collagen I-Matrigel composite extracellular matrix (ECM). The composite ECM was used to determine the influence of the local collagen fiber orientation on the collective intravasation ability of tumor cells. We found that the local fiber alignment enhanced cell-ECM interactions. Specifically, metastatic MDA-MB-231 breast cancer cells followed the local fiber alignment direction during the intravasation into rigid Matrigel (?10 mg/mL protein concentration). Twit Text FOAVip Oriented collagen fibers direct tumor cell intravasation ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27663743 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27663743 #FOAvip English Wikipedia <ref>{{Cite pmid|27663743 }}</ref> Oriented collagen fibers direct tumor cell intravasation #MMPMID27663743 Han W ; Chen S ; Yuan W ; Fan Q ; Tian J ; Wang X ; Chen L ; Zhang X ; Wei W ; Liu R ; Qu J ; Jiao Y ; Austin RH ; Liu L Proc Natl Acad Sci U S A 2016[Oct]; 113 (40 ): 11208-11213 PMID27663743 show ga In this work, we constructed a Collagen I-Matrigel composite extracellular matrix (ECM). The composite ECM was used to determine the influence of the local collagen fiber orientation on the collective intravasation ability of tumor cells. We found that the local fiber alignment enhanced cell-ECM interactions. Specifically, metastatic MDA-MB-231 breast cancer cells followed the local fiber alignment direction during the intravasation into rigid Matrigel (?10 mg/mL protein concentration). |Biopsy [MESH] |Cell Line, Tumor [MESH] |Cell Proliferation [MESH] |Collagen/*chemistry [MESH] |Disease Progression [MESH] |Extracellular Matrix/metabolism [MESH] |Female [MESH] |Humans [MESH] |Neoplasm Metastasis/*pathology [MESH] |Neoplasms/*pathology [MESH]Oriented collagen fibers direct tumor cell intravasation (epmc).pdf DeepDyve Pubget Overpricing