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2017 ; 22
(5
): e586-e594
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Oral manifestations of Diabetes Mellitus A systematic review
#MMPMID28809366
Mauri-Obradors E
; Estrugo-Devesa A
; Jané-Salas E
; Viñas M
; López-López J
Med Oral Patol Oral Cir Bucal
2017[Sep]; 22
(5
): e586-e594
PMID28809366
show ga
BACKGROUND: Diabetes Mellitus has become a global epidemic and presents many
complications, usually proportional to the degree and duration of hyperglycemia.
The aim of this systematic review was to investigate the different oral
manifestations associated with Diabetes Mellitus. MATERIAL AND METHODS: A MEDLINE
search for "Diabetes Mellitus and oral manifestations" was performed. A further
search was conducted for "diabetes" and its individual oral manifestation.
Inclusion criteria were as follows: human clinical studies with a minimum of 30
patients; studies published in relevant scientific journals between January 1998
and January 2016. Nineteen studies fulfilled the inclusion criteria and were
analyzed, assessing the strength of scientific evidence according to
recommendations made by the Centre for Evidence-Based Medicine, Oxford (OCEBM),
which permits adequate assessment of prevalence studies. RESULTS: A total 3,712
patients (2,084 diabetics) were included in the studies reviewed. Of the 19
studies analyzed, 4 were longitudinal studies and 15 cross-sectional studies.
Periodontal disease, periapical lesions, xerostomia and taste disturbance were
more prevalent among diabetic patients. An association between diabetes and
caries and mucosal lesions proved positive in 5 out of 10 studies. CONCLUSIONS:
Despite multiple oral manifestations associated with DM, awareness of the
associations between diabetes, oral health, and general health is inadequate. It
is necessary for doctors and dentists to be aware of the various oral
manifestations of diabetes in order to make an early diagnosis.