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10.1002/jnr.23767 http://scihub22266oqcxt.onion/10.1002/jnr.23767 C5548626!5548626 !27413006     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27413006 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Neurosci+Res 2017 ; 95 (12 ): 2325-2335 Nephropedia Template TP {{tp|p=27413006 |t=2017. Optogenetic study of networks in epilepsy |pdf=|usr=}}{{27413006 }} gab.com Text Optogenetic study of networks in epilepsy JO: J Neurosci Res http://www.kidney.de/pget.php?&tw=1&pmid=27413006 #FOAvip Currently, approximately 30% of patients with epilepsy do not have adequate seizure control. A greater understanding of the underlying mechanisms by which seizures start or propagate could lead to new therapeutic strategies. The recent development of optogenetics, because of its unprecedented precision for controlling activity within distinct neuronal populations, has revolutionized neuroscience, including epilepsy research. This Review discusses recent breakthroughs made with optogenetics in epilepsy research. These breakthroughs include new insights into the key roles that different cell types play in mediating seizures as well as in the development of epilepsy. Subsequently, we discuss how targeting different brain regions and cell populations has opened up the possibility of highly specific therapies that can stop seizures on demand. Finally, we illustrate how combining newly available neuroscience tools with whole-brain imaging techniques will allow researchers to understand better the spread of seizures on a network level. © 2016 The Authors. Journal of Neuroscience Research Published by Wiley Periodicals, Inc. Twit Text FOAVip Optogenetic study of networks in epilepsy ????J Neurosci Res http://www.kidney.de/pget.php?&tw=1&pmid=27413006 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27413006 #FOAvip English Wikipedia <ref>{{Cite pmid|27413006 }}</ref> Optogenetic study of networks in epilepsy #MMPMID27413006 Choy M ; Duffy BA ; Lee JH J Neurosci Res 2017[Dec]; 95 (12 ): 2325-2335 PMID27413006 show ga Currently, approximately 30% of patients with epilepsy do not have adequate seizure control. A greater understanding of the underlying mechanisms by which seizures start or propagate could lead to new therapeutic strategies. The recent development of optogenetics, because of its unprecedented precision for controlling activity within distinct neuronal populations, has revolutionized neuroscience, including epilepsy research. This Review discusses recent breakthroughs made with optogenetics in epilepsy research. These breakthroughs include new insights into the key roles that different cell types play in mediating seizures as well as in the development of epilepsy. Subsequently, we discuss how targeting different brain regions and cell populations has opened up the possibility of highly specific therapies that can stop seizures on demand. Finally, we illustrate how combining newly available neuroscience tools with whole-brain imaging techniques will allow researchers to understand better the spread of seizures on a network level. © 2016 The Authors. Journal of Neuroscience Research Published by Wiley Periodicals, Inc. |*Epilepsy [MESH] |*Optogenetics [MESH] |Animals [MESH]Optogenetic study of networks in epilepsy (epmc).pdf DeepDyve Pubget Overpricing