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2016 ; 40
(3
): E8
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Optical technologies for intraoperative neurosurgical guidance
#MMPMID26926066
Valdés PA
; Roberts DW
; Lu FK
; Golby A
Neurosurg Focus
2016[Mar]; 40
(3
): E8
PMID26926066
show ga
Biomedical optics is a broadly interdisciplinary field at the interface of
optical engineering, biophysics, computer science, medicine, biology, and
chemistry, helping us understand light-tissue interactions to create applications
with diagnostic and therapeutic value in medicine. Implementation of biomedical
optics tools and principles has had a notable scientific and clinical resurgence
in recent years in the neurosurgical community. This is in great part due to work
in fluorescence-guided surgery of brain tumors leading to reports of significant
improvement in maximizing the rates of gross-total resection. Multiple additional
optical technologies have been implemented clinically, including diffuse
reflectance spectroscopy and imaging, optical coherence tomography, Raman
spectroscopy and imaging, and advanced quantitative methods, including
quantitative fluorescence and lifetime imaging. Here we present a clinically
relevant and technologically informed overview and discussion of some of the
major clinical implementations of optical technologies as intraoperative guidance
tools in neurosurgery.
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