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2017 ; 15
(3
): 380-387
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Ophthalmologic manifestations in patients with inflammatory bowel disease
#MMPMID28670235
Lee HJ
; Song HJ
; Jeong JH
; Kim HU
; Boo SJ
; Na SY
Intest Res
2017[Jul]; 15
(3
): 380-387
PMID28670235
show ga
BACKGROUND/AIMS: Inflammatory bowel disease (IBD), including Crohn's disease (CD)
and ulcerative colitis (UC), has been reported to have various ophthalmologic
manifestations. The aim of this study was to evaluate the prevalence of
ophthalmologic manifestations associated with IBD in Korea. METHODS: Sixty-one
patients were examined between May 2013 and October 2014. We performed complete
ophthalmologic examinations. RESULTS: Findings included 36 patients with CD and
25 with UC. The mean age of the patients was 34±16 years and disease duration was
45.3±23.9 months. Ophthalmologic manifestations were positive in 44 cases.
Primary complication was diagnosed in 5 cases, as follows; iritis in 2 cases,
episcleritis in one case, iritis with optic neuritis in 1 case, and serous
retinal detachment in 1 case, without secondary complications. The most common
coincidental complication was dry eye syndrome (DES), in 35 patients (57.4%). The
prevalence of DES in the control group was 21.3%. The proportion of DES in
patients with IBD was significantly higher than in the control group (P=0.002).
CONCLUSIONS: Ophthalmologic manifestations were high (72.1%) in IBD patients.
Clinically significant primary ocular inflammation occurred in 8.2% of patients.
The most common complication was DES. There was a higher rate of DES in patients
with IBD compared to the control group. Evaluation of the eye should be a routine
component in patients with IBD.