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10.1097/IAE.0000000000000716

http://scihub22266oqcxt.onion/10.1097/IAE.0000000000000716
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suck abstract from ncbi


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pmid26308529
      Retina 2015 ; 35 (11 ): 2371-6
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  • OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF DIABETIC RETINOPATHY #MMPMID26308529
  • Hwang TS ; Jia Y ; Gao SS ; Bailey ST ; Lauer AK ; Flaxel CJ ; Wilson DJ ; Huang D
  • Retina 2015[Nov]; 35 (11 ): 2371-6 PMID26308529 show ga
  • PURPOSE: To describe the optical coherence tomography angiography features of diabetic retinopathy. METHODS: Using a 70 kHz optical coherence tomography and the split-spectrum amplitude decorrelation angiography algorithm, 6 mm × 6 mm 3-dimensional angiograms of the macula of 4 patients with diabetic retinopathy were obtained and compared with fluorescein angiography for features cataloged by the Early Treatment of Diabetic Retinopathy Study. RESULTS: Optical coherence tomography angiography detected enlargement and distortion of the foveal avascular zone, retinal capillary dropout, and pruning of arteriolar branches. Areas of capillary loss obscured by fluorescein leakage on fluorescein angiography were more clearly defined on optical coherence tomography angiography. Some areas of focal leakage on fluorescein angiography that were thought to be microaneurysms were found to be small tufts of neovascularization that extended above the inner limiting membrane. CONCLUSION: Optical coherence tomography angiography does not show leakage but can better delineate areas of capillary dropout and detect early retinal neovascularization. This new noninvasive angiography technology may be useful for routine surveillance of proliferative and ischemic changes in diabetic retinopathy.
  • |*Fluorescein Angiography [MESH]
  • |*Tomography, Optical Coherence [MESH]
  • |Adult [MESH]
  • |Aneurysm/*diagnosis [MESH]
  • |Blood Flow Velocity [MESH]
  • |Capillaries/pathology [MESH]
  • |Capillary Permeability [MESH]
  • |Diabetic Retinopathy/*diagnosis/physiopathology [MESH]
  • |Female [MESH]
  • |Fovea Centralis/blood supply [MESH]
  • |Humans [MESH]
  • |Ischemia/*diagnosis [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Regional Blood Flow [MESH]
  • |Retinal Neovascularization/*diagnosis [MESH]


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