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10.1016/j.freeradbiomed.2015.04.035 http://scihub22266oqcxt.onion/10.1016/j.freeradbiomed.2015.04.035 C4628893!4628893 !25975985     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25975985 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25975985 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Free+Radic+Biol+Med 2015 ; 88 (Pt B ): 268-274 Nephropedia Template TP {{tp|p=25975985 |t=2015. Nrf2 promotes survival following exposure to ionizing radiation |pdf=|usr=}}{{25975985 }} gab.com Text Nrf2 promotes survival following exposure to ionizing radiation JO: Free Radic Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=25975985 #FOAvip Nrf2 is a transcription factor that promotes antioxidant and drug-metabolizing gene expression. It also regulates the transcription of genes involved in carbohydrate and lipid metabolism, NADPH regeneration, and heme and iron metabolism, as well as proteasome metabolism. Emerging research has identified Nrf2 as a critical factor for promoting survival of mammalian cells subjected to ionizing radiation. At a mechanistic level, Nrf2 promotes the repair of DNA damage and drives detoxification of superoxide that is generated hours to days after irradiation. This review summarizes research in these areas and discusses targeting of Nrf2 in radiation-resistant cancer and Nrf2?s role in mitigating acute radiation syndrome. Twit Text FOAVip Nrf2 promotes survival following exposure to ionizing radiation ????Free Radic Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=25975985 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25975985 #FOAvip English Wikipedia <ref>{{Cite pmid|25975985 }}</ref> Nrf2 promotes survival following exposure to ionizing radiation #MMPMID25975985 Sekhar KR ; Freeman ML Free Radic Biol Med 2015[Nov]; 88 (Pt B ): 268-274 PMID25975985 show ga Nrf2 is a transcription factor that promotes antioxidant and drug-metabolizing gene expression. It also regulates the transcription of genes involved in carbohydrate and lipid metabolism, NADPH regeneration, and heme and iron metabolism, as well as proteasome metabolism. Emerging research has identified Nrf2 as a critical factor for promoting survival of mammalian cells subjected to ionizing radiation. At a mechanistic level, Nrf2 promotes the repair of DNA damage and drives detoxification of superoxide that is generated hours to days after irradiation. This review summarizes research in these areas and discusses targeting of Nrf2 in radiation-resistant cancer and Nrf2?s role in mitigating acute radiation syndrome. |*Radiation, Ionizing [MESH] |Animals [MESH] |Cell Survival/*physiology/radiation effects [MESH] |DNA Repair/*physiology [MESH] |Humans [MESH] |NF-E2-Related Factor 2/*metabolism [MESH]Nrf2 promotes survival following exposure to ionizing radiation (epmc).pdf DeepDyve Pubget Overpricing