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10.1097/MOT.0b013e328342551c

http://scihub22266oqcxt.onion/10.1097/MOT.0b013e328342551c
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C4855507!4855507 !21150607
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suck abstract from ncbi


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pmid21150607
      Curr+Opin+Organ+Transplant 2011 ; 16 (1 ): 61-8
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  • Novel functions of B cells in transplantation #MMPMID21150607
  • Platt JL ; Tsuji S ; Cascalho M
  • Curr Opin Organ Transplant 2011[Feb]; 16 (1 ): 61-8 PMID21150607 show ga
  • PURPOSE OF REVIEW: This manuscript reviews current knowledge and recent findings regarding antibody-independent functions of B cells in transplantation. RECENT FINDINGS: Until recently the functions of B cells in transplantation have been attributed almost entirely to the antibodies they produce. However, the results of recent trials of B-cell-depleting agents for treatment of antibody-mediated rejection as well as auto-immune disease raised awareness that B cells mediate functions independent of antibody synthesis. SUMMARY: These 'nonclassical' functions place B cells at the center of immune regulation with the power to enhance or inhibit immunity.
  • |*Transplantation Immunology [MESH]
  • |Animals [MESH]
  • |Antibodies/immunology [MESH]
  • |Antibody Formation [MESH]
  • |B-Lymphocytes/*immunology [MESH]
  • |Graft Survival/immunology [MESH]
  • |Humans [MESH]


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