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2016 ; 10
(2
): 193-204
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Novel approaches to treating Clostridium difficile-associated colitis
#MMPMID26643655
Padua D
; Pothoulakis C
Expert Rev Gastroenterol Hepatol
2016[]; 10
(2
): 193-204
PMID26643655
show ga
Clostridium difficile is being recognized as a growing threat to many health-care
systems. Epidemiology data shows that infection rates are soaring and the disease
burden is increasing. Despite the efficacy of standard treatments, it is becoming
evident that novel therapeutics will be required to tackle this disease. These
new treatments aim to enhance the intestinal microbial barrier, activate the
immune system and neutralize the toxins that mediate this disease. Many of these
therapies are still in the beginning stages of investigation, however, in the
next few years, more clinical data will become available to help implement many
of these exciting new therapeutic approaches.
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