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10.1016/j.tem.2015.02.006 http://scihub22266oqcxt.onion/10.1016/j.tem.2015.02.006 C4435535!4435535 !25805408     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25805408 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25805408 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Trends+Endocrinol+Metab 2015 ; 26 (5 ): 248-55 Nephropedia Template TP {{tp|p=25805408 |t=2015. Notch signaling as a novel regulator of metabolism |pdf=|usr=}}{{25805408 }} gab.com Text Notch signaling as a novel regulator of metabolism JO: Trends Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=25805408 #FOAvip Evolutionarily unprepared for modern high-calorie diets and sedentary lifestyles, humans are now unprecedentedly susceptible to metabolic disorders such as obesity, type 2 diabetes (T2D), nonalcoholic fatty liver, and cardiovascular disease. These metabolic conditions are intertwined, together known as metabolic syndrome, and compromise human life quality as well as lives. Notch signaling, a fundamental signal transduction pathway critical for cell-cell communication and development, has recently been recognized as a key player in metabolism. This review summarizes the emerging roles of Notch signaling in regulating the metabolism of various cell and tissue types, with emphasis on the underlying molecular mechanisms and the potential of targeting this signal axis to treat metabolic diseases. Twit Text FOAVip Notch signaling as a novel regulator of metabolism ????Trends Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=25805408 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25805408 #FOAvip English Wikipedia <ref>{{Cite pmid|25805408 }}</ref> Notch signaling as a novel regulator of metabolism #MMPMID25805408 Bi P ; Kuang S Trends Endocrinol Metab 2015[May]; 26 (5 ): 248-55 PMID25805408 show ga Evolutionarily unprepared for modern high-calorie diets and sedentary lifestyles, humans are now unprecedentedly susceptible to metabolic disorders such as obesity, type 2 diabetes (T2D), nonalcoholic fatty liver, and cardiovascular disease. These metabolic conditions are intertwined, together known as metabolic syndrome, and compromise human life quality as well as lives. Notch signaling, a fundamental signal transduction pathway critical for cell-cell communication and development, has recently been recognized as a key player in metabolism. This review summarizes the emerging roles of Notch signaling in regulating the metabolism of various cell and tissue types, with emphasis on the underlying molecular mechanisms and the potential of targeting this signal axis to treat metabolic diseases. |3T3-L1 Cells [MESH] |Adipocytes/metabolism [MESH] |Animals [MESH] |Homeostasis [MESH] |Humans [MESH] |Immunity [MESH] |Insulin [MESH] |Insulin Resistance [MESH] |Metabolism/*physiology [MESH] |Mice [MESH] |Muscle, Skeletal/metabolism [MESH] |Nervous System [MESH] |Receptors, Notch/*physiology [MESH]Notch signaling as a novel regulator of metabolism (epmc).pdf DeepDyve Pubget Overpricing