Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26526819
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26526819
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Rev+Pain
2007 ; 1
(1
): 2-6
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Normal Pain Transmission
#MMPMID26526819
Urch C
Rev Pain
2007[Aug]; 1
(1
): 2-6
PMID26526819
show ga
Acute (normal) pain transmission is part of a survival response to prevent tissue
damage and attend to and protect damaged tissue.A cycle of afferent transmission,
response to stimuli, followed by temporary hypersensitivity, then attenuation and
resolution occurs.Primary afferent, spinal cord ascending and descending pathways
are fixed; however the response elicited is highly dynamic and not a linear
relationship with input intensity.Somatic inputs are topographically accurate, in
contrast to diffuse visceral inputs.Primary afferents code differentially for
stimuli (heat, acid, pressure etc) and intensity.The dorsal horn allows extensive
modulation of initial inputs, either excitation or inhibition.Higher CNS areas
allow extensive modulation of inputs, account for the conscious recognition of
pain: the intensity, location, emotional and memory aspects.Descending pathways
arising from midbrain regions can be inhibitory or excitatory.