Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26112334
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Neurosci+Methods
2015 ; 253
(ä): 90-100
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Non-invasive primate head restraint using thermoplastic masks
#MMPMID26112334
Drucker CB
; Carlson ML
; Toda K
; DeWind NK
; Platt ML
J Neurosci Methods
2015[Sep]; 253
(ä): 90-100
PMID26112334
show ga
BACKGROUND: The success of many neuroscientific studies depends upon adequate
head fixation of awake, behaving animals. Typically, this is achieved by
surgically affixing a head-restraint prosthesis to the skull. NEW METHOD: Here we
report the use of thermoplastic masks to non-invasively restrain monkeys' heads.
Mesh thermoplastic sheets become pliable when heated and can then be molded to an
individual monkey's head. After cooling, the custom mask retains this shape
indefinitely for day-to-day use. RESULTS: We successfully trained rhesus macaques
(Macaca mulatta) to perform cognitive tasks while wearing thermoplastic masks.
Using these masks, we achieved a level of head stability sufficient for
high-resolution eye-tracking and intracranial electrophysiology. COMPARISON WITH
EXISTING METHOD: Compared with traditional head-posts, we find that thermoplastic
masks perform at least as well during infrared eye-tracking and single-neuron
recordings, allow for clearer magnetic resonance image acquisition, enable freer
placement of a transcranial magnetic stimulation coil, and impose lower financial
and time costs on the lab. CONCLUSIONS: We conclude that thermoplastic masks are
a viable non-invasive form of primate head restraint that enable a wide range of
neuroscientific experiments.