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10.12659/AJCR.894601 http://scihub22266oqcxt.onion/10.12659/AJCR.894601 C4504409!4504409 !26167722     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26167722 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+J+Case+Rep 2015 ; 16 (ä): 449-53 Nephropedia Template TP {{tp|p=26167722 |t=2015. Non-Systemic Vasculitic Neuropathy: An Enigmatic Clinical Entity |pdf=|usr=}}{{26167722 }} gab.com Text Non-Systemic Vasculitic Neuropathy: An Enigmatic Clinical Entity JO: Am J Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=26167722 #FOAvip BACKGROUND: Non-systemic vasculitic peripheral neuropathy is a rare condition characterized by necrotizing inflammation resulting in luminal narrowing of the vasa nervorum, leading to ischemic injury to peripheral nerves. Here, we present the case of 63-year-old woman with subacute onset of severe hyperesthesia of the lower extremities accompanied by foot drop. CASE REPORT: A 63-year-old woman with prolonged history of uncontrolled diabetes mellitus presented with subacute onset of severe bilateral lower extremity hyperesthesia and motor weakness along with left-sided foot drop. She had multiple emergency room visits with no relief of her symptoms. High doses of analgesics were insufficient to control pain. Laboratory tests were positive only for high erythrocyte sedimentation rate and C-reactive protein. A skin biopsy obtained 5 cm above the left lateral malleolus revealed medium-sized dermal vasculitis with dense mononuclear infiltrate. Electromyography showed peripheral neuropathy. A nerve biopsy was needed to reveal the exact diagnosis. CONCLUSIONS: Diagnosis of non-systemic vasculitic peripheral neuropathy can be delayed or missed in patients with uncontrolled diabetes mellitus, leading to significant morbidity. Elevated markers of inflammation in the absence of a possible explanation should prompt the clinician to perform a nerve biopsy; however, it is an invasive procedure and is associated with complications of post-neuropathic pain and delayed wound healing. Magnetic resonance angiography of the lower limbs, if combined with skin biopsy, can save the patient from undergoing nerve biopsy. Twit Text FOAVip Non-Systemic Vasculitic Neuropathy: An Enigmatic Clinical Entity ????Am J Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=26167722 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26167722 #FOAvip English Wikipedia <ref>{{Cite pmid|26167722 }}</ref> Non-Systemic Vasculitic Neuropathy: An Enigmatic Clinical Entity #MMPMID26167722 Lubana SS ; Singh N ; Sanelli-Russo S ; Abrudescu A Am J Case Rep 2015[Jul]; 16 (ä): 449-53 PMID26167722 show ga BACKGROUND: Non-systemic vasculitic peripheral neuropathy is a rare condition characterized by necrotizing inflammation resulting in luminal narrowing of the vasa nervorum, leading to ischemic injury to peripheral nerves. Here, we present the case of 63-year-old woman with subacute onset of severe hyperesthesia of the lower extremities accompanied by foot drop. CASE REPORT: A 63-year-old woman with prolonged history of uncontrolled diabetes mellitus presented with subacute onset of severe bilateral lower extremity hyperesthesia and motor weakness along with left-sided foot drop. She had multiple emergency room visits with no relief of her symptoms. High doses of analgesics were insufficient to control pain. Laboratory tests were positive only for high erythrocyte sedimentation rate and C-reactive protein. A skin biopsy obtained 5 cm above the left lateral malleolus revealed medium-sized dermal vasculitis with dense mononuclear infiltrate. Electromyography showed peripheral neuropathy. A nerve biopsy was needed to reveal the exact diagnosis. CONCLUSIONS: Diagnosis of non-systemic vasculitic peripheral neuropathy can be delayed or missed in patients with uncontrolled diabetes mellitus, leading to significant morbidity. Elevated markers of inflammation in the absence of a possible explanation should prompt the clinician to perform a nerve biopsy; however, it is an invasive procedure and is associated with complications of post-neuropathic pain and delayed wound healing. Magnetic resonance angiography of the lower limbs, if combined with skin biopsy, can save the patient from undergoing nerve biopsy. |Angiography [MESH] |Biopsy [MESH] |Electromyography [MESH] |Female [MESH] |Femoral Nerve/*pathology [MESH] |Femoral Neuropathy/complications/*diagnosis [MESH] |Humans [MESH] |Middle Aged [MESH] |Vasa Nervorum/*pathology [MESH]Non-Systemic Vasculitic Neuropathy: An Enigmatic Clinical Entity (epmc).pdf DeepDyve Pubget Overpricing