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2020 ; 12
(2
): 136-139
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Nicotine and smoking in the COVID-19 era
#MMPMID32626554
Tajlil A
; Ghaffari S
; Pourafkari L
; Mashayekhi S
; Roshanravan N
J Cardiovasc Thorac Res
2020[]; 12
(2
): 136-139
PMID32626554
show ga
Introduction: The knowledge regarding the demographic characteristics of patients
with Covid-19 and risk factors distribution is still evolving. Considering the
role of cigarette smoking in the pathogenesis of lung diseases and the effect of
nicotine on expression of the entry receptor for severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), it is important to determine the
implications of smoking in COVID-19. Methods: In this brief report, by using the
published articles in the literature, we aimed to compare the reported prevalence
of smoking in patients with COVID-19 to the prevalence of smoking in the general
population of the corresponding report. Binomial tests were conducted and a P
value of less than 0.05 was considered statistically significant. Results: Among
the screened papers, we found 12 peer-reviewed articles in which epidemiological
characteristics of COVID-19 patients, including smoking status, were stated.
Based on the descriptive reports of characteristics of COVID-19 patients, we
observed a significantly lower proportion of COVID-19 patients with smoking
history compared to what is expected, given the population average for each
study's geographic area. Conclusion: This analysis of available data showed a
lower prevalence of smoking in COVID-19 patients in comparison to the regional
average. Considering the limitations of the study, the results should be
interpreted with great caution and be viewed just as a preliminary report to
motivate related basic and clinical researches.