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10.4161/23723548.2014.968073

http://scihub22266oqcxt.onion/10.4161/23723548.2014.968073
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C4905238!4905238!27308399
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suck abstract from ncbi


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pmid27308399      Mol+Cell+Oncol 2015 ; 2 (1): ä
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  • Nfkb1 suppresses DNA alkylation-induced tumor formation #MMPMID27308399
  • Schmitt AM; Yamini B
  • Mol Cell Oncol 2015[Jan]; 2 (1): ä PMID27308399show ga
  • NF-?B proteins play a complex role in modulating carcinogenesis following DNA damage. Previous work identified p50/NF-?B1 as a necessary factor in the cytotoxic response to alkylation damage. Recently, these findings were extended to demonstrate that in the setting of alkylation damage, this NF-?B subunit acts as a haploinsufficient tumor suppressor that prevents hematologic malignancy formation.
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