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10.1002/jrsm.1191

http://scihub22266oqcxt.onion/10.1002/jrsm.1191
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C4964911!4964911 !26610739
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suck abstract from ncbi


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pmid26610739
      Res+Synth+Methods 2016 ; 7 (3 ): 314-28
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  • New models for describing outliers in meta-analysis #MMPMID26610739
  • Baker R ; Jackson D
  • Res Synth Methods 2016[Sep]; 7 (3 ): 314-28 PMID26610739 show ga
  • An unobserved random effect is often used to describe the between-study variation that is apparent in meta-analysis datasets. A normally distributed random effect is conventionally used for this purpose. When outliers or other unusual estimates are included in the analysis, the use of alternative random effect distributions has previously been proposed. Instead of adopting the usual hierarchical approach to modelling between-study variation, and so directly modelling the study specific true underling effects, we propose two new marginal distributions for modelling heterogeneous datasets. These two distributions are suggested because numerical integration is not needed to evaluate the likelihood. This makes the computation required when fitting our models much more robust. The properties of the new distributions are described, and the methodology is exemplified by fitting models to four datasets. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd.
  • |*Meta-Analysis as Topic [MESH]
  • |*Models, Statistical [MESH]
  • |Algorithms [MESH]
  • |Cognition Disorders/drug therapy [MESH]
  • |Cytidine Diphosphate Choline/therapeutic use [MESH]
  • |Dental Caries/prevention & control [MESH]
  • |Fluorides/therapeutic use [MESH]
  • |Humans [MESH]
  • |Hypercholesterolemia/drug therapy [MESH]
  • |Monte Carlo Method [MESH]
  • |Paroxetine/therapeutic use [MESH]
  • |Placebos [MESH]
  • |Pravastatin/therapeutic use [MESH]
  • |Regression Analysis [MESH]
  • |Research Design [MESH]
  • |Software [MESH]
  • |Statistics as Topic [MESH]


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