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10.1038/bjc.2014.471

http://scihub22266oqcxt.onion/10.1038/bjc.2014.471
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C4453439!4453439 !25211658
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suck abstract from ncbi


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pmid25211658
      Br+J+Cancer 2015 ; 112 (2 ): 227-31
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  • New insights into signalling-pathway alterations in rhabdomyosarcoma #MMPMID25211658
  • Zhu B ; Davie JK
  • Br J Cancer 2015[Jan]; 112 (2 ): 227-31 PMID25211658 show ga
  • Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and young adults. Several recent studies have shed new light on the alterations in signalling pathways and the downstream effects of these pathway alterations in RMS. Many of these effects converge on the fibroblast growth factor and insulin-like growth-factor pathways. These new findings improve the current understanding of RMS, thus offering novel potential therapeutic targets and strategies that may improve the outcome for patients with RMS.
  • |*Signal Transduction [MESH]
  • |Animals [MESH]
  • |Cell Cycle [MESH]
  • |Gene Expression Regulation, Neoplastic [MESH]
  • |Humans [MESH]
  • |Intercellular Signaling Peptides and Proteins/physiology [MESH]
  • |Muscle Neoplasms/genetics/*metabolism/pathology [MESH]
  • |Oncogenes [MESH]
  • |Rhabdomyosarcoma/genetics/*metabolism/pathology [MESH]


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