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10.1155/2017/1609575 http://scihub22266oqcxt.onion/10.1155/2017/1609575 C5376429!5376429 !28401148     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28401148 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biomed+Res+Int 2017 ; 2017 (ä): 1609575 Nephropedia Template TP {{tp|p=28401148 |t=2017. New Insights into the Epigenetics of Hepatocellular Carcinoma |pdf=|usr=}}{{28401148 }} gab.com Text New Insights into the Epigenetics of Hepatocellular Carcinoma JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=28401148 #FOAvip Hepatocellular Carcinoma (HCC) is one of the most predominant malignancies with high fatality rate. This deadly cancer is rising at an alarming rate because it is quite resistant to radio- and chemotherapy. Different epigenetic mechanisms such as histone modifications, DNA methylation, chromatin remodeling, and expression of noncoding RNAs drive the cell proliferation, invasion, metastasis, initiation, progression, and development of HCC. These epigenetic alterations because of potential reversibility open way towards the development of biomarkers and therapeutics. The contribution of these epigenetic changes to HCC development has not been thoroughly explored yet. Further research on HCC epigenetics is necessary to better understand novel molecular-targeted HCC treatment and prevention. This review highlights latest research progress and current updates regarding epigenetics of HCC, biomarker discovery, and future preventive and therapeutic strategies to combat the increasing risk of HCC. Twit Text FOAVip New Insights into the Epigenetics of Hepatocellular Carcinoma ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=28401148 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28401148 #FOAvip English Wikipedia <ref>{{Cite pmid|28401148 }}</ref> New Insights into the Epigenetics of Hepatocellular Carcinoma #MMPMID28401148 Wahid B ; Ali A ; Rafique S ; Idrees M Biomed Res Int 2017[]; 2017 (ä): 1609575 PMID28401148 show ga Hepatocellular Carcinoma (HCC) is one of the most predominant malignancies with high fatality rate. This deadly cancer is rising at an alarming rate because it is quite resistant to radio- and chemotherapy. Different epigenetic mechanisms such as histone modifications, DNA methylation, chromatin remodeling, and expression of noncoding RNAs drive the cell proliferation, invasion, metastasis, initiation, progression, and development of HCC. These epigenetic alterations because of potential reversibility open way towards the development of biomarkers and therapeutics. The contribution of these epigenetic changes to HCC development has not been thoroughly explored yet. Further research on HCC epigenetics is necessary to better understand novel molecular-targeted HCC treatment and prevention. This review highlights latest research progress and current updates regarding epigenetics of HCC, biomarker discovery, and future preventive and therapeutic strategies to combat the increasing risk of HCC. |*Epigenesis, Genetic [MESH] |Carcinoma, Hepatocellular/*genetics/pathology [MESH] |Cell Proliferation/genetics [MESH] |Chromatin Assembly and Disassembly/genetics [MESH] |DNA Methylation/*genetics [MESH] |Gene Expression Regulation, Neoplastic [MESH] |Humans [MESH] |Liver Neoplasms/*genetics/pathology [MESH] |Neoplasm Invasiveness/genetics [MESH]New Insights into the Epigenetics of Hepatocellular Carcinoma (epmc).pdf DeepDyve Pubget Overpricing