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10.1155/2017/2896380 http://scihub22266oqcxt.onion/10.1155/2017/2896380 C5361057!5361057 !28373994     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28373994 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Immunol+Res 2017 ; 2017 (ä): 2896380 Nephropedia Template TP {{tp|p=28373994 |t=2017. Neutrophil Extracellular Traps and Microcrystals |pdf=|usr=}}{{28373994 }} gab.com Text Neutrophil Extracellular Traps and Microcrystals JO: J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=28373994 #FOAvip Neutrophil extracellular traps represent a fascinating mechanism by which PMNs entrap extracellular microbes. The primary purpose of this innate immune mechanism is thought to localize the infection at an early stage. Interestingly, the ability of different microcrystals to induce NET formation has been recently described. Microcrystals are insoluble crystals with a size of 1-100 micrometers that have different composition and shape. Microcrystals have it in common that they irritate phagocytes including PMNs and typically trigger an inflammatory response. This review is the first to summarize observations with regard to PMN activation and NET release induced by microcrystals. Gout-causing monosodium urate crystals, pseudogout-causing calcium pyrophosphate dehydrate crystals, cholesterol crystals associated with atherosclerosis, silicosis-causing silica crystals, and adjuvant alum crystals are discussed. Twit Text FOAVip Neutrophil Extracellular Traps and Microcrystals ????J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=28373994 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28373994 #FOAvip English Wikipedia <ref>{{Cite pmid|28373994 }}</ref> Neutrophil Extracellular Traps and Microcrystals #MMPMID28373994 Rada B J Immunol Res 2017[]; 2017 (ä): 2896380 PMID28373994 show ga Neutrophil extracellular traps represent a fascinating mechanism by which PMNs entrap extracellular microbes. The primary purpose of this innate immune mechanism is thought to localize the infection at an early stage. Interestingly, the ability of different microcrystals to induce NET formation has been recently described. Microcrystals are insoluble crystals with a size of 1-100 micrometers that have different composition and shape. Microcrystals have it in common that they irritate phagocytes including PMNs and typically trigger an inflammatory response. This review is the first to summarize observations with regard to PMN activation and NET release induced by microcrystals. Gout-causing monosodium urate crystals, pseudogout-causing calcium pyrophosphate dehydrate crystals, cholesterol crystals associated with atherosclerosis, silicosis-causing silica crystals, and adjuvant alum crystals are discussed. |Alum Compounds/chemistry [MESH] |Animals [MESH] |Calcium Pyrophosphate/chemistry [MESH] |Cholesterol/chemistry [MESH] |Crystallization [MESH] |Extracellular Traps/*immunology [MESH] |Humans [MESH] |Neutrophil Activation [MESH] |Neutrophils/immunology/*physiology [MESH] |Particle Size [MESH] |Silicon Dioxide/chemistry [MESH]Neutrophil Extracellular Traps and Microcrystals (epmc).pdf DeepDyve Pubget Overpricing