Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27412684
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27412684
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Neurotherapeutics
2016 ; 13
(3
): 461-70
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Neurological Complications of Ebola Virus Infection
#MMPMID27412684
Billioux BJ
; Smith B
; Nath A
Neurotherapeutics
2016[Jul]; 13
(3
): 461-70
PMID27412684
show ga
Ebola virus disease is one of the deadliest pathogens known to man, with a
mortality rate between 25-90% depending on the species and outbreak of Ebola.
Typically, it presents with fever, headache, voluminous vomiting and diarrhea,
and can progress to a hemorrhagic illness; neurologic symptoms, including
meningoencephalitis, seizures, and coma, can also occur. Recently, an outbreak
occurred in West Africa, affecting > 28,000 people, and killing > 11,000. Owing
to the magnitude of this outbreak, and the large number (>17,000) of Ebola
survivors, the medical and scientific communities are learning much more about
the acute manifestations and sequelae of Ebola. A number of neurologic
complications can occur after Ebola, such as seizures, memory loss, headaches,
cranial nerve abnormalities, and tremor. Ebola may also persist in some
immunologically privileged sites, including the central nervous system, and can
rarely lead to relapse in disease. Owing to these findings, it is important that
survivors are evaluated and monitored for neurologic symptoms. Much is unknown
about this disease, and treatment remains largely supportive; however, with
ongoing clinical and basic science, the mechanisms of how Ebola affects the
central nervous system and how it persists after acute disease will hopefully
become more clear, and better treatments and clinical practices for Ebola
patients will be developed.
|Brain/pathology/physiopathology/virology
[MESH]
|Cranial Nerve Diseases/virology
[MESH]
|Disease Outbreaks
[MESH]
|Disease Transmission, Infectious
[MESH]
|Headache/virology
[MESH]
|Hemorrhagic Fever, Ebola/*complications/epidemiology/physiopathology/prevention &
control
[MESH]
|Humans
[MESH]
|Memory Disorders/virology
[MESH]
|Meningoencephalitis/virology
[MESH]
|Nervous System Diseases/pathology/physiopathology/*virology
[MESH]
free
free
free
