Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1212/WNL.0000000000002418 http://scihub22266oqcxt.onion/10.1212/WNL.0000000000002418 C4793783!4793783 !26843559     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26843559 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26843559 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Neurology 2016 ; 86 (9 ): 800-7 Nephropedia Template TP {{tp|p=26843559 |t=2016. Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy |pdf=|usr=}}{{26843559 }} gab.com Text Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy JO: Neurology http://www.kidney.de/pget.php?&tw=1&pmid=26843559 #FOAvip OBJECTIVE: We report the clinical and serologic features of Japanese patients with chronic inflammatory demyelinating polyneuropathy (CIDP) displaying anti-neurofascin-155 (NF155) immunoglobulin G4 (IgG4) antibodies. METHODS: In sera from 533 patients with CIDP, anti-NF155 IgG4 antibodies were detected by ELISA. Binding of IgG antibodies to central and peripheral nerves was tested. RESULTS: Anti-NF155 IgG4 antibodies were identified in 38 patients (7%) with CIDP, but not in disease controls or normal participants. These patients were younger at onset as compared to 100 anti-NF155-negative patients with CIDP. Twenty-eight patients (74%) presented with sensory ataxia, 16 (42%) showed tremor, 5 (13%) presented with cerebellar ataxia associated with nystagmus, 3 (8%) had demyelinating lesions in the CNS, and 20 of 25 (80%) had poor response to IV immunoglobulin. The clinical features of the antibody-positive patients were statistically more frequent as compared to negative patients with CIDP (n = 100). Anti-NF155 IgG antibodies targeted similarly central and peripheral paranodes. CONCLUSION: Anti-NF155 IgG4 antibodies were associated with a subgroup of patients with CIDP showing a younger age at onset, ataxia, tremor, CNS demyelination, and a poor response to IV immunoglobulin. The autoantibodies may serve as a biomarker to improve patients' diagnosis and guide treatments. Twit Text FOAVip Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy ????Neurology http://www.kidney.de/pget.php?&tw=1&pmid=26843559 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26843559 #FOAvip English Wikipedia <ref>{{Cite pmid|26843559 }}</ref> Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy #MMPMID26843559 Devaux JJ ; Miura Y ; Fukami Y ; Inoue T ; Manso C ; Belghazi M ; Sekiguchi K ; Kokubun N ; Ichikawa H ; Wong AH ; Yuki N Neurology 2016[Mar]; 86 (9 ): 800-7 PMID26843559 show ga OBJECTIVE: We report the clinical and serologic features of Japanese patients with chronic inflammatory demyelinating polyneuropathy (CIDP) displaying anti-neurofascin-155 (NF155) immunoglobulin G4 (IgG4) antibodies. METHODS: In sera from 533 patients with CIDP, anti-NF155 IgG4 antibodies were detected by ELISA. Binding of IgG antibodies to central and peripheral nerves was tested. RESULTS: Anti-NF155 IgG4 antibodies were identified in 38 patients (7%) with CIDP, but not in disease controls or normal participants. These patients were younger at onset as compared to 100 anti-NF155-negative patients with CIDP. Twenty-eight patients (74%) presented with sensory ataxia, 16 (42%) showed tremor, 5 (13%) presented with cerebellar ataxia associated with nystagmus, 3 (8%) had demyelinating lesions in the CNS, and 20 of 25 (80%) had poor response to IV immunoglobulin. The clinical features of the antibody-positive patients were statistically more frequent as compared to negative patients with CIDP (n = 100). Anti-NF155 IgG antibodies targeted similarly central and peripheral paranodes. CONCLUSION: Anti-NF155 IgG4 antibodies were associated with a subgroup of patients with CIDP showing a younger age at onset, ataxia, tremor, CNS demyelination, and a poor response to IV immunoglobulin. The autoantibodies may serve as a biomarker to improve patients' diagnosis and guide treatments. |Adolescent [MESH] |Adult [MESH] |Age Distribution [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Autoantibodies/*blood/immunology [MESH] |Biomarkers/*blood [MESH] |Cell Adhesion Molecules/*blood/immunology [MESH] |Child [MESH] |Female [MESH] |Humans [MESH] |Immunoglobulin G/*blood/immunology [MESH] |Incidence [MESH] |Japan/epidemiology [MESH] |Male [MESH] |Middle Aged [MESH] |Nerve Growth Factors/*blood/immunology [MESH] |Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/*blood/diagnosis/*epidemiology [MESH] |Risk Assessment/methods [MESH]Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropa(epmc).pdf DeepDyve Pubget Overpricing