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2016 ; 28
(7
): ä Nephropedia Template TP
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Neuroendocrine Regulation of Metabolism
#MMPMID27114114
Cornejo MP
; Hentges ST
; Maliqueo M
; Coirini H
; Becu-Villalobos D
; Elias CF
J Neuroendocrinol
2016[Jul]; 28
(7
): ä PMID27114114
show ga
Given the current environment in most developed countries, it is a challenge to
maintain a good balance between calories consumed and calories burned, although
maintenance of metabolic balance is key to good health. Therefore, understanding
how metabolic regulation is achieved and how the dysregulation of metabolism
affects health is an area of intense research. Most studies focus on the
hypothalamus, which is a brain area that acts as a key regulator of metabolism.
Among the nuclei that comprise the hypothalamus, the arcuate nucleus is one of
the major mediators in the regulation of food intake. The regulation of energy
balance is also a key factor ensuring the maintenance of any species as a result
of the dependence of reproduction on energy stores. Adequate levels of energy
reserves are necessary for the proper functioning of the
hypothalamic-pituitary-gonadal axis. This review discusses valuable data
presented in the 2015 edition of the International Workshop of Neuroendocrinology
concerning the fundamental nature of the hormonal regulation of the hypothalamus
and the impact on energy balance and reproduction.
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