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2017 ; 2017
(ä): 5646348
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Neurocardiology: Cardiovascular Changes and Specific Brain Region Infarcts
#MMPMID28758117
Zou R
; Shi W
; Tao J
; Li H
; Lin X
; Yang S
; Hua P
Biomed Res Int
2017[]; 2017
(ä): 5646348
PMID28758117
show ga
There are complex and dynamic reflex control networks between the heart and the
brain, including cardiac and intrathoracic ganglia, spinal cord, brainstem, and
central nucleus. Recent literature based on animal model and clinical trials
indicates a close link between cardiac function and nervous systems. It is
noteworthy that the autonomic nervous-based therapeutics has shown great
potential in the management of atrial fibrillation, ventricular arrhythmia, and
myocardial remodeling. However, the potential mechanisms of postoperative brain
injury and cardiovascular changes, particularly heart rate variability and the
presence of arrhythmias, are not understood. In this chapter, we will describe
mechanisms of brain damage undergoing cardiac surgery and focus on the
interaction between cardiovascular changes and damage to specific brain regions.