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2017 ; 12
(1
): 1-6
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Neonatal Hypoxic-ischemic Encephalopathy: A Radiological Review
#MMPMID28553370
Bano S
; Chaudhary V
; Garga UC
J Pediatr Neurosci
2017[Jan]; 12
(1
): 1-6
PMID28553370
show ga
Neonatal hypoxic-ischemic encephalopathy (HIE) is a devastating condition that
may result in death or severe neurologic deficits in children. Neuroimaging with
cranial ultrasound (US), computed tomography and magnetic resonance imaging are
valuable tools in the workup of patients with HIE. The pattern of brain injury
depends on the severity and duration of hypoxia and degree of brain maturation.
Mild to moderate HI injury results in periventricular leukomalacia and germinal
matrix bleed in preterm neonates, and parasagittal watershed infarcts in
full-term neonates. Severe HI injury involves deep gray matter in both term and
preterm infants. Treatment of HIE is largely supportive. The current article
reviews the etiopathophysiology and clinical manifestations of HIE, role of
imaging in the evaluation of the condition, patterns of brain injury in term and
preterm neonates, the treatment and the prognosis.