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2014 ; 21
(11
): 591-6
Nephropedia Template TP
Stamm AW
; Nguyen ND
; Seicol BJ
; Fagan A
; Oh A
; Drumm M
; Lundt M
; Stickgold R
; Wamsley EJ
Learn Mem
2014[Nov]; 21
(11
): 591-6
PMID25320351
show ga
Post-learning sleep is beneficial for human memory. However, it may be that not
all memories benefit equally from sleep. Here, we manipulated a spatial learning
task using monetary reward and performance feedback, asking whether enhancing the
salience of the task would augment overnight memory consolidation and alter its
incorporation into dreaming. Contrary to our hypothesis, we found that the
addition of reward impaired overnight consolidation of spatial memory. Our
findings seemingly contradict prior reports that enhancing the reward value of
learned information augments sleep-dependent memory processing. Given that the
reward followed a negative reinforcement paradigm, consolidation may have been
impaired via a stress-related mechanism.