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10.1038/nrg3734 http://scihub22266oqcxt.onion/10.1038/nrg3734 C4912034!4912034 !24776769     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24776769 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Nat+Rev+Genet 2014 ; 15 (6 ): 379-93 Nephropedia Template TP {{tp|p=24776769 |t=2014. Natural selection and infectious disease in human populations |pdf=|usr=}}{{24776769 }} gab.com Text Natural selection and infectious disease in human populations JO: Nat Rev Genet http://www.kidney.de/pget.php?&tw=1&pmid=24776769 #FOAvip The ancient biological 'arms race' between microbial pathogens and humans has shaped genetic variation in modern populations, and this has important implications for the growing field of medical genomics. As humans migrated throughout the world, populations encountered distinct pathogens, and natural selection increased the prevalence of alleles that are advantageous in the new ecosystems in both host and pathogens. This ancient history now influences human infectious disease susceptibility and microbiome homeostasis, and contributes to common diseases that show geographical disparities, such as autoimmune and metabolic disorders. Using new high-throughput technologies, analytical methods and expanding public data resources, the investigation of natural selection is leading to new insights into the function and dysfunction of human biology. Twit Text FOAVip Natural selection and infectious disease in human populations ????Nat Rev Genet http://www.kidney.de/pget.php?&tw=1&pmid=24776769 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24776769 #FOAvip English Wikipedia <ref>{{Cite pmid|24776769 }}</ref> Natural selection and infectious disease in human populations #MMPMID24776769 Karlsson EK ; Kwiatkowski DP ; Sabeti PC Nat Rev Genet 2014[Jun]; 15 (6 ): 379-93 PMID24776769 show ga The ancient biological 'arms race' between microbial pathogens and humans has shaped genetic variation in modern populations, and this has important implications for the growing field of medical genomics. As humans migrated throughout the world, populations encountered distinct pathogens, and natural selection increased the prevalence of alleles that are advantageous in the new ecosystems in both host and pathogens. This ancient history now influences human infectious disease susceptibility and microbiome homeostasis, and contributes to common diseases that show geographical disparities, such as autoimmune and metabolic disorders. Using new high-throughput technologies, analytical methods and expanding public data resources, the investigation of natural selection is leading to new insights into the function and dysfunction of human biology. |*Selection, Genetic [MESH] |Communicable Diseases, Emerging/epidemiology/*genetics/metabolism [MESH]Natural selection and infectious disease in human populations (epmc).pdf DeepDyve Pubget Overpricing