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2015 ; 34
(3
): 1097-105
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Nanotechnology applications in hematological malignancies (Review)
#MMPMID26134389
Samir A
; Elgamal BM
; Gabr H
; Sabaawy HE
Oncol Rep
2015[Sep]; 34
(3
): 1097-105
PMID26134389
show ga
A major limitation to current cancer therapies is the development of
therapy-related side-effects and dose limiting complications. Moreover, a better
understanding of the biology of cancer cells and the mechanisms of resistance to
therapy is rapidly developing. The translation of advanced knowledge and
discoveries achieved at the molecular level must be supported by advanced
diagnostic, therapeutic and delivery technologies to translate these discoveries
into useful tools that are essential in achieving progress in the war against
cancer. Nanotechnology can play an essential role in this aspect providing a
transforming technology that can translate the basic and clinical findings into
novel diagnostic, therapeutic and preventive tools useful in different types of
cancer. Hematological malignancies represent a specific class of cancer, which
attracts special attention in the applications of nanotechnology for cancer
diagnosis and treatment. The aim of the present review is to elucidate the
emerging applications of nanotechnology in cancer management and describe the
potentials of nanotechnology in changing the key fundamental aspects of
hematological malignancy diagnosis, treatment and follow-up.
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